If you are unsure, consult the extensive help screens, which explain the statistical reasoning in plain language. InStat helps you pick an appropriate test by asking questions about your data. You don't have to know the name of the test you need. You'll master the program in just a few minutes - really. InStat conquers the learning curve by escorting you through statistical analyses. Preview how different graphs look with your data before deciding.Five reasons why you should choose InStat: Much easier to create the graph you want since you don't pick the graph type until after entering data.Many dialogs now a have checkbox to make your choices on that dialog (or tab) become the defaults when you use that dialog in the future. Choose the size, shape and color of selected data points right from the data table.Paste link data or results copied from Prism, and those values will be hot linked.Want to plot alternating columns as dotted lines? Now you can do it in one step. Nonparametric calculations are way way faster!.Faster in many ways: saving, graphing, exporting and closing.View and edit all of your column titles at once.Create data sets with up to 256 subcolumns (up from 52) to allow repeated measures 2 way ANOVA with more subjects.Enter data in up to 256 data set columns (up from 52 in Prism 5).Fit to models defined by implicit and differential equations.

Dunnett's test now can handle up to 256 groups (up from 20).

Test main or simple effects after two-way ANOVA.

New multiple comparisons test: Holm-Sidak.

New approach: Fisher’s unprotected Least Significant Difference (LSD).

Graph 95% CI of difference between means.

Exact (multiplicity adjusted) P values with Bonferroni, Tukey and Dunnett's tests.

Multiple tests (one-per row) with optional correction for multiple comparisons.

Kolmogorov-Smirnov test (alternative to Mann-Whitney).

Greenhouse-Geisser correction in one-way repeated measures ANOVA.

Calculate and graph 95% CI of difference between medians with Mann-Whitney test.

Calculate and graph 95% CI of median with Wilcoxon test.

Detect outliers in a column of data using Grubbs' test.

Two-way ANOVA with repeated measures in both factors.

And you can try the Prism 6 demo without removing Prism 5. The basic interface and organization of the program has not changed, so you can switch to Prism 6 with almost no learning curve. It has more statistical clout, can make more kinds of graphs, and is even more efficient to use. Prism 6 is a big upgrade with many improvements.

Graphpad prism 6 demo